The best time of the year to embark on your Mississippi cruise is in spring or fall. What is the best time to go on a Mississippi River cruise? Adventures through America’s heartland await. Join an immersive excursion in every port tailor-made for you and return onboard the iconic paddle-wheeler to sophisticated entertainment and fine dining. You can pick from four incredible itineraries lasting from 8 to 9 days and watch the striking scenery change with each destination, all from the comfort of your luxurious river boat.Įxplore Civil War battlegrounds, indulge in Southern cooking, and enjoy the sounds of New Orleans’s jazz on your once-in-a-lifetime Mississippi River cruise. The voyage will take you through picturesque port stops like Nottoway, Baton Rouge, Natchez, Vicksburg, and New Orleans. Louis, Missouri, to New Orleans, Louisiana, adventures, culture, and history are packed into every bend of the river. Join American Queen Voyages aboard a Lower Mississippi River voyage, America’s most iconic river boat adventure.

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